Chromosome 6 (human)


In the human genome, chromosome 6 is one of the 23 chromosomes. It is a submetacentric chromosome, found within group C of the human karyotype. As with all autosomes, somatic cells carry two copies of chromosome 6, while gametes carry only one copy.

Chromosome 6 is approximately 170 Mbp (million base pairs) in length, comprising ~5.5-6% of the haploid genome
Chromosome 6 has approximately 1100-1600 genes

Chromosome 6 contains the major histocompatibility complex, which contains over 100 genes related to the immune response and thus plays a vital role in organ transplantation.

Significant genes (and some related genetic diseases) on chromosome 6 include: