Chromosome 3 (human)

In the human genome, chromosome 3 is one of the 23 chromosomes. It is a metacentric chromosome, found within group A of the human karyotype. As with all autosomes, somatic cells carry two copies of chromosome 3, while gametes carry only one copy.

Chromosome 3 is approximately 200 Mbp (million base pairs) in length, comprising ~6.5% of the haploid genome
Chromosome 3 has approximately 1100-1500 genes

Significant genes (and some related genetic diseases) on chromosome 3 include:

  • RHO (genetic locus: 3q21-q24) encodes the rhodopsin visual pigment. Defects in the gene cause retinitis pigmentosa (incurable genetic blindness)